XO-Cargo™ for Aesthetic Clinics
A powerful, non-invasive exosome treatment. Clinically proven results without irritation.
The most efficacious aesthetic actives often carry the greatest risk of sensitivity. XO-Cargo™ eliminates that trade-off – clinically proven, dermatologist verified, and designed to perform as a powerful standalone treatment or to complement and amplify in-clinic procedures.
XO-Cargo™ ME
The In-Clinic Exosome.
Purified exosome performance.
XO-Cargo™ ME — purified, naturally loaded milk exosomes — delivers clinically proven improvement in appearance of skin elasticity and wrinkles, with a 0.0 HRIPT irritation score. Containing naturally occurring proteins, lipids, and fatty acids, ME is effective both as a powerful in-clinic treatment and an at home-care product.
Clinical Performance — 28 days
- 2.8x Greater reduction in the appearance of wrinkles vs base serum
- +29% Improvement in appearance of skin elasticity (+15% vs base serum)
- –34% Reduction in the appearance of wrinkles (-22% vs base serum)
XO-Cargo™ AA
Peptide Loaded Exosomes
Cosmetics’ first peptide loaded exosomes.
For clinics where rapid elasticity improvement is the clinical priority, XO-Cargo™ AA is a pure milk exosome precision loaded with a proprietary dermal elasticity peptide. Delivering targeted action with market-leading improvements in the appearance of skin elasticity at Day 14 and with a 0.0 HRIPT irritation score.
Clinical Performance — 14 days
- +42% Improvement in appearance of skin elasticity (+24 vs base serum)
- 4x Faster at improving appearance of skin elasticity than leading peptide actives
- 4x More effective at improving appearance of skin elasticity than the closest benchmark active at Day 14
The Clinical Advantage:
Why Clinics choose XO-Cargo™
Complements existing protocols
Designed to work as a powerful non-invasive treatment, applied directly to skin, in addition to complimenting and amplifying other exisiting procedures.
No irritation
0.0 HRIPT across all subjects. No redness, no sensitivity – clinically proven to deliver results without the irritation risk associated with traditional active delivery.
Peer-reviewed
science
Three decades of peer-reviewed research. Two independent GBA Polska RDBPC clinical studies. Substantiated claims ready for patient communication.
Exclusively available to clinics at launch
XO-Cargo™ AA is currently exclusively available to aesthetic clinics.
Why Milk Exosomes
Not all exosomes are equal.
Aesthetic clinics are increasingly approached by exosome products – plant-derived (which are not true exosomes), synthetic, and MSC-derived. The differences matter. Milk exosomes are mammalian in origin, sharing the same fundamental biology as human exosomes – structurally compatible in a way plant-derived alternatives cannot replicate. MSC-derived exosomes are already prohibited in cosmetic applications in the EU and US. XO-Cargo™ is neither. It is independently validated, commercially available, and manufactured to a fixed specification from a single auditable US source.
Clinic Supply
XO-Cargo™ clinic-use milk exosomes are supplied lyophilized in individually filled, sterilized vials. They ship with an Activation Serum, which is added to the vial to disperse the exosomes for use — ready for single-treatment and multi-use clinical applications. Available in boxes of 12.
How to use
XO-Cargo™ clinic-use exosomes are prepared for use by adding an XO-Cargo™ Activation Serum to the vial containing XO-Cargo exosomes, shaking gently until fully dispersed, and applying immediately to clean skin. Our team will provide full instructions for use (IFU), training materials and patient support literature.
Join our founding
clinical cohort
Trials currently underway.
We are building a founding cohort of leading aesthetic practices to validate XO-Cargo™ in clinic. Participating clinics receive product to conduct their own small trial, with our full clinical and technical support.
Scientific Literature
Peer-reviewed research and technical publications on milk exosome biology and delivery.
Bovine Milk Exosomes in human skin aging (clinical + in vitro data)
Large-scale isolation of milk exosomes for skincare (mechanistic + application focused approach)
Nanotheranostics method publication
Lyophilization method publication
Milk EVs review publication
