The XO-Cargo™ Range
Purified, naturally loaded and peptide loaded milk exosomes
From inherent performance to precision targeted results, every ingredient in the XO-Cargo range is built on the same biological platform — highly purified, batch-validated bovine milk exosomes. Produced at industrial scale in a dedicated clean-room in Roanoke, Virginia.
The XO-Cargo™ Range
XO-Cargo™ ME
Purified, naturally loaded milk exosomes.
XO-Cargo ME is our purified, naturally loaded milk exosome ingredient. Containing naturally occurring proteins, lipids, and fatty acids it delivers clinically proven improvements in the appearance of skin elasticity and wrinkles at day 28, with results that continue to build over time. The milk exosome is the active ingredient.
Clinical Performance — 28 days
- 2.8x Greater reduction in the appearance of wrinkles vs base serum
- +29% Improvement in appearance of skin elasticity (+15% vs base serum)
- –34% Reduction in the appearance of wrinkles (-22% vs base serum)
- 100% Subject Satisfaction
- 0.0 HRIPT Irritation Score
Why choose XO-Cargo™ ME
Inherent performance
The exosome is the active — delivering cargo directly to the skin.
Outperforms leading anti-aging actives
At 0.01% w/w, XO-Cargo ME delivers greater improvement in the appearance of skin elasticity than leading anti-aging actives at their standard inclusion levels — at a fraction of the concentration.
Accelerating trajectory
The improvement in the appearance of skin elasticity builds to +29% at Day 28. Improvement in appearance of skin elasticity, firmness and wrinkles continues to strengthen with continued use.
Powerful non-invasive treatment
Designed to work as a powerful non-invasive treatment, applied directly to skin, in addition to complimenting and amplifying other exisiting protocols.
Biological compatibility advantage
Bovine milk exosomes share the same fundamental biology as human exosomes. A fundamental advantage over plant- derived and synthetic alternatives.
Formulation
XO-Cargo™ ME is supplied as a free-flowing lyophilized powder. Drop-in compatible with oil-based, anhydrous and emulsion formulation bases — no specialist equipment or reformulation required. Thermally stable through standard processing conditions.
- Inclusion 0.01% w/w
- Yield Up to 100,000 applications per gram
- Stability >30 months ambient
- Room Temperature Stability No cold chain required
- Scalable Supply Produced in a purpose built, clean-room facility. Full batch documentation.
- Formulation-ready Suitable for oil, emulsion, and anhydrous formulations.
- Format Lyophilized powder
- INCI Milk Exosomes #35079
Who it’s for
Aesthetic Clinics
A powerful non-invasive treatment. 0.0 HRIPT across all subjects. Dermatologist verified.
Brands & OEMs
For brands that lead. Visible results at Day 28 positioning. Drop-in compatible.
XO-Cargo™ AA
Cosmetics first Peptide Loaded Exosomes
XO-Cargo AA is our peptide loaded milk exosome ingredient. A proprietary dermal elasticity peptide, precision loaded inside an XO-Cargo milk exosome, delivering rapid clinically proven improvements in appearance of skin elasticity at day 14. This proprietary peptide was developed over three decades of peer-reviewed research at the Fralin Biomedical Research Institute, Virginia Tech.
Clinical Performance — 14 days
- +42% Improvement in appearance of skin elasticity (+24 vs base serum)
- 4x Faster at improving appearance of skin elasticity than leading peptide actives
- 4x More effective at improving appearance of skin elasticity than the closest benchmark active at Day 14
- 0.0 HRIPT irritation score
Speed vs Leading Actives – Skin Elasticity Improvement
At equivalent or shorter timepoints, no published benchmark approaches XO-Cargo™ AA’s level of performance.
Why choose XO-Cargo™ AA
In-clinic aesthetic treatment
The in-clinic exosome treatment that supports rapid results for customers.
Visible Rapid Results
Visible improvement in appearance of skin elasticity at Day 14. Four times faster than leading peptide actives.
Encapsulated delivery
The active is encapsulated within the exosome in a stable form.
Biological compatibility advantage
Bovine milk exosomes share the same fundamental biology as human exosomes. A fundamental advantage over plant- derived and synthetic alternatives.
Formulation
XO-Cargo™ AA is supplied as a free-flowing lyophilized powder. Drop-in compatible with oil-based, anhydrous and emulsion formulation bases. No specialist equipment or reformulation required.
- Inclusion 0.01% w/w
- Yield Up to 100,000 applications per gram
- Stability >30 months ambient
- Room Temperature Stability No cold chain required
- Scalable Supply Produced in a purpose built, clean-room facility. Full batch documentation.
- Formulation-ready Suitable for oil, emulsion, and anhydrous formulations.
- Format Lyophilized powder
- INCI Milk Exosomes #35079
Who it’s for
Aesthetic Clinics
XO-Cargo™ AA is currently available exclusively to aesthetic clinics. The fastest clinically proven elasticity active on the market.
Cosmetic Brands & OEMs
Available selectively upon consultation. Express your interest to be considered for priority access.
In Development
The platform is expanding
Two further precision-loaded variants are in active development — extending clinically proven exosome delivery into new cosmetic categories.
XO-Cargo™ ST
Precision-loaded milk exosome variant targeting improvement in the appearance of skin tone, redness and blemishes.
XO-Cargo™ HR
Precision-loaded milk exosome variant for cosmetic hair-care applications.
Four reasons to load your active
Enhanced Efficacy
The exosome’s natural delivery capability amplifies the performance of any loaded active.
Zero Irritation
Loaded actives don’t contact the skin surface as free molecules, removing the potential for sensitivity associated with traditional delivery methods. 0.0 HRIPT validated across all subjects.
Long-Term Stability
Lyophilization locks the loaded active inside the exosome for more than 30 months at ambient temperature. Many free actives degrade within hours in formulation.
Cost Efficiency
Actives precision-loaded into XO-Cargo™ exosomes achieve clinically proven results at significantly lower inclusion levels than free actives require — reducing formulation cost without compromising performance.
How it works
- Share your active under NDA. We assess suitability, and after feasibility is confirmed provide a fully detailed and costed Statement of Work for loading your active.
- We precision-load your active into XO-Cargo™ exosomes, lyophilize and package it for dispatch.
- You receive a fully characterised, loaded exosome ingredient — ready for formulation.
Available for peptides, vitamins, botanical extracts and other cosmetic actives. Loading feasibility confirmed prior to production. Full encapsulation characterisation provided with every batch. Commercial terms, MOQ and eligible actives: speak directly with our team.
